Decreased CTCF Expression Directs DNA Hypermethylation Events in Cancer

ABSTRACT: Methylation profiling of immortalized human prostate epithelial cells after CTCF knockdown by short hairpin RNA. Methylated DNA was immunoprecipitated with anti-methylcytosine antibodies from genomic DNA and detected by Affymetrix CytoScanHD chips. Methylated DNA was purified by 5-mC antibodies and Affymetrix CytoScanHD arrays were performed according to the manufacturer's protocols.

ORGANISM(S): Homo sapiens

PROVIDER: GSE93328 | GEO | 2019/02/20

REPOSITORIES: GEO