High-throughput RNA-sequencing of preadipocyte subsets in obese mice

ABSTRACT: We identified a population of obesity-promoted adipogenic preadipocytes that co-expressed Fabp4 and ICAM-1. Fabp4-Cre;mTmG mice were treated with high-fat diet for 16 weeks. The inguinal adipose tissues were collected and digested to obtain vascular and stromal fractions (SVF). The mature adipocytes, CD31-CD45-Sca-1+PDGFR-α+ICAM-1+EGFP+, CD31-CD45-Sca-1+PDGFR-α+ICAM-1+EGFP-, CD31-CD45-Sca-1+PDGFR-α+ICAM-1- cell population were isolated for RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE93697 | GEO | 2025/12/31

REPOSITORIES: GEO