Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microarray analysis of microRNAs in CSF and blood of SAH patients

ABSTRACT: The aim of the analysis is to identify changes in the microRNAs expression in early phase after SAH.

ORGANISM(S): Homo sapiens

PROVIDER: GSE93746 | GEO | 2018/02/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Fishing for SAM/SAH-binding proteins

Project description:The aim of the project was to identify S-adenodsyl methionine-binding proteins expressed in D. melanogaster S2 cells. For this puprose a capture compund reagent carrying a SAH-affinity group, a biotin group for enrichment and a cross-linking moiety consisting of either benzophenone or a nitrobenzene.

2019-02-25 | PXD006245 | Pride

Gene expression data from mouse brain endothelial cells after SAH

Project description:SAH pathophysiology includes blood-brain barrier (BBB) disruption. Gene expression changes at the endothelial cell level may provide insight into BBB pathophysiology. We used microarray gene expression data comparing freshly isolated brain endothelial cells isolated from Sham or SAH mice.

2021-04-12 | GSE155137 | GEO

Five microRNAs in serum are able to differentiate breast cancer patients from healthy individuals

Project description:Breast Cancer is the cancer with most incidence and mortality in women. microRNAs are emerging as novel prognosis/diagnostic tools. Our aim was to identify a serum microRNA signature useful to predict cancer development. We focused on studying the expression levels of 30 microRNAs in the serum of 96 breast cancer patients versus 92 control individuals. Bioinformatic studies provide a microRNA signature, designated as a predictor, based upon the expression levels of 5 microRNAs. Then, we tested the predictor in a group of 60 randomly chosen women. Lastly, a proteomic study unveiled the over-expression and down-regulation of proteins differently expressed in the serum of breast cancer patients versus that of control individuals. Twenty-six microRNAs differentiate cancer tissue from healthy tissue and 16 microRNAs differentiate the serum of cancer patients from that of the control group. The tissue expression of miR-99a-5p, mir-497-5p, miR-362, and miR-1274, and the serum levels of miR-141 correlated with patient survival. Moreover, the predictor consisting of mir-125b-5p, miR-29c-3p, mir-16-5p, miR-1260, and miR-451a was able to differentiate breast cancer patients from controls. The predictor was validated in 20 new cases of breast cancer patients and tested in 60 volunteer women, assigning 11 out of 60 women to the cancer group. An association of low levels of mir-16-5p with a high content of CD44 protein in serum was found. Circulating microRNAs in serum can represent biomarkers for cancer prediction. Their clinical relevance and use of the predictor here described might be of potential importance for breast cancer prediction.

2020-09-18 | PXD020795 | Pride

Transcription profiling by array of the effect of SAH on brain cells in white matter region of mice

Project description:Using the SAH model to conduct experiments, set 5 groups of experimental groups and 5 groups of control groups. Studying the effects on the white matter cells of normal mice and the mice with SAH

2019-10-10 | E-MTAB-8407 | biostudies-arrayexpress

Coleofasciculus sp. SAH DSM 104245

Project description:cyanosphere of Coleofasciculus sp. SAH DSM 104254 culture

| PRJNA993447 | ENA

Halorubrum aethiopicum strain:SAH-A6

Project description:Halorubrum aethiopicum strain:SAH-A6 Genome sequencing and assembly

| PRJNA302707 | ENA

Burkholderia orbicola strain:SAH 5-5

Project description:Burkholderia orbicola strain:SAH 5-5 Genome sequencing

| PRJNA1287893 | ENA

Epigenomics of Patient Outcomes after Aneurysmal SAH

Project description:Epigenomics of Patient Outcomes after Aneurysmal SAH

| PRJNA610915 | ENA

Epigenomics of Patient Outcomes after Aneurysmal SAH

Project description:Epigenomics of Patient Outcomes after Aneurysmal SAH

| PRJNA610914 | ENA

Human blood microRNAs and their potential effect on mosquitoes

Project description:Blood is a rich source of proteins for mosquitoes, but also contains many other molecules such as microRNAs (miRNAs). Here, we found that human blood miRNAs are transported in abundance into the fat body tissue of Aedes aegypti, a key metabolic center in post-blood feeding reproductive events, where they target and regulate mosquito genes.

2021-06-28 | PXD023190 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data