Characterization of three Epithelial Ovarian Cancer cell lines resistant to cisplatin (microRNA).

ABSTRACT: Epithelial ovarian cancer (EOC) represents the gynecologic cancer with the highest mortality rate. Despite a high initial response to chemotherapy, the majority of patients with advanced EOC relapses and subsequently develops chemoresistance that results in treatment failure and death of the patient. AIM: we have generated an isogenic model of PT-resistance in a panel of 3 EOC cell lines. microRNA profiling was used to identify new molecular pathway that regulate chemoresistance.

ORGANISM(S): Homo sapiens

PROVIDER: GSE93794 | GEO | 2017/07/24

SECONDARY ACCESSION(S): PRJNA362359

REPOSITORIES: GEO