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Altered expression of genes in HOXD-AS1 knockdown prostate cancer cells

ABSTRACT: Castration-resistant prostate cancer (CRPC) that arise after the failure of androgen deprivation therapy is a leading cause of deaths in prostate cancer patients. HOXD-AS1 is reported to play a role in bladder cancer and neuroblastoma. However, its function and underlying mechanism in CRPC remains unknown. The goal of this study is to identify the target genes of HOXD-AS1 in prostate cancer. Our results inditcate that the genes regulated by HOXD-S1 involved in a variety of biological functions, such as proliferation and and Androgen Receptor signaling.

ORGANISM(S): Homo sapiens

PROVIDER: GSE93928 | GEO | 2017/08/18

SECONDARY ACCESSION(S): PRJNA362851

REPOSITORIES: GEO

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