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Chaperone dependent coordination of nutrient sensing and energy metabolism by mTORC2

ABSTRACT: mTORC2 senses nutrients and coordinates substrate metabolism and macromolecule synthesis program with the availability of external nutrient availability. Knockdown of mTORC2 components and its chaperone partners impairs both nutrient sensing and downstrem metabolism/growth programs.

ORGANISM(S): Mus musculus

PROVIDER: GSE93948 | GEO | 2020/01/23

REPOSITORIES: GEO

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mTORC2-NDRG1-Cdc42 axis couples fasting to mitochondrial fission

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