Expression data from normal human spheroid-forming keratinocytes in monolayer mass culture and from corresponding cornified-like spheroid ring structures.
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ABSTRACT: 3-D suspension culture differs considerably from monolayer culture in regards to cell architecture, cell to cell contact, and cell to matrix interactions. These factors play a regulatory role in epithelial stem cell homeostasis and influence epidermal stem cells on their decision to remain quiescent or to activate self-renewal. We used microarrays to determine the global programme of gene expression underlying spheroid ring formation and identified distinct gene programs involved in this process.
ORGANISM(S): Homo sapiens
PROVIDER: GSE94244 | GEO | 2021/01/31
REPOSITORIES: GEO
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