Transcriptomics,Genomics

Dataset Information

28

Dynamic gene expression response to altered gravity in human T cells (sounding rocket flight)


ABSTRACT: We investigated differentially regulated genes in human Jurkat T lymphocytic cells in 20s and 5min microgravity and in hypergravity and compared expression profiles to identify potential gravity-regulated genes and adaptation processes. Overall design: Human Jurkat T cells were exposed to altered gravity during a sounding rocket flight

INSTRUMENT(S): [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]

SUBMITTER: Cora S. Thiel  

PROVIDER: GSE94255 | GEO | 2017-08-11

SECONDARY ACCESSION(S): PRJNA369305

REPOSITORIES: GEO

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Publications


We investigated the dynamics of immediate and initial gene expression response to different gravitational environments in human Jurkat T lymphocytic cells and compared expression profiles to identify potential gravity-regulated genes and adaptation processes. We used the Affymetrix GeneChip® Human Transcriptome Array 2.0 containing 44,699 protein coding genes and 22,829 non-protein coding genes and performed the experiments during a parabolic flight and a suborbital ballistic rocket mission to c  ...[more]

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