Project description:For the study of possible downstream targets of Meis2b, we compared the following expression profiles: 48hpf whole larvae of meis2bs988/s988 to meis2b+/+ siblings, whole heart of 3 wpf meis2bs988/s988 to meis2b+/s988 siblings, atria of 3 mpf meis2bs988/s988 to meis2bs988/+ siblings, and ventricle to atrium of 3 mpf WT zebrafish.
Project description:Comparison of total RNA of atrial and ventricular chambers from adult zebrafish heart. The goal was to identify chamber specific transcripts and atrial enriched transcripts that can be linked to atrial or ventricular septal defects in mammals.
Project description:Comparison of the meis2b+ and the meis2b- halves of the atrium of the adult zebrafish atrium reveals the existence of two different transcriptional domains. These two domains analogous to that of the two atria in terrestrial vertebrates
