Genomics

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Transcriptional profiles of PBMCs from pigs infected with three genetically diverse PRRSV strains


ABSTRACT: Porcine reproductive and respiratory syndrome virus (PRRSV) is a causative agent of an important infectious disease causing serious economic losses to swine industry called PRRS (porcine reproductive and respiratory syndrome). The clinical signs of this syndrome indcude respiratory disorders, abortions and variable mortality in piglets. To compare the virulence of highly diverse East European strains belonging to subtype 2 (Russian strain ILI and Belarusian strain BOR) and Danish strain from classical subtype 1 (DAN) the experimental study enrolling infection of piglets was performed. Gene expression profiles of peripheral blood mononuclear cells (PBMC) of piglets infected with three PRRSV strains vs control piglets were analysed by microarray analysis to gain insight into transcriptome changes after PRRSV infection.

ORGANISM(S): Sus scrofa

PROVIDER: GSE95213 | GEO | 2017/02/23

SECONDARY ACCESSION(S): PRJNA376436

REPOSITORIES: GEO

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