Genomics

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Skin inflammation exacerbates food allergy symptoms in epicutaneously sensitized mice


ABSTRACT: Cutaneous exposure to food antigen through impaired skin barrier has been shown to induce epicutaneous sensitization, and thereby cause IgE-mediated food allergy. We examined whether skin barrier impairment deteriorated food allergy symptoms in epicutaneously sensitized mice. To clarify the association between skin inflammation and food allergy symptoms, we analyzed gene expression at skin lesions using a GeneChip.

ORGANISM(S): Mus musculus

PROVIDER: GSE95278 | GEO | 2017/06/30

SECONDARY ACCESSION(S): PRJNA376548

REPOSITORIES: GEO

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