Transcriptomics

Dataset Information

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Expression data from ribosomal protein (RP) L23 (RPL23)-KD and NC SKM-1 cells.


ABSTRACT: Ribosomal protein (RP) L23 is a negative regulator of cell apoptosis. RPL23 overexpression is associated with abnormal apoptotic resistance in CD34+ cells derived from patients with higher-risk myelodysplastic syndrome (MDS). However, the mechanism underlying RPL23-induced apoptotic resistance in higher-risk MDS patients is poorly understood. Gene microarray analysis between RPL23-knockdown (RPL23-KD) and matched control cells (RPL23-NC) was performed to detail global gene expression profiles and to identify differentially expressed genes and potentially involved pathways associated with RPL23 knockdown.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95348 | GEO | 2017/02/25

SECONDARY ACCESSION(S): PRJNA376708

REPOSITORIES: GEO

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