Genomics

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ChIPSeq data from melanoma cancer cell line CHL-1 after Bromodomain and extra terminal (Bet) domain inhibitor treatment


ABSTRACT: Bromodomain and extra terminal domain (BET) inhibition reduces occupancy of BET-family proteins at promoter and enhancer sites finally leading to genome wide changes in gene transcription. We used ChIPSeq profiling to investigate genome wide changes in promoter and enhancer occupancy induced by BET inhibitors BAY 1238097 and OTX-015, respectively.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95585 | GEO | 2017/09/30

SECONDARY ACCESSION(S): PRJNA377564

REPOSITORIES: GEO

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