Genomics

Dataset Information

0

Expression data from Drosophila tumor models


ABSTRACT: Epithelial tumors can progress from a benign tissue overgrowth (hyperplasia) to a malignant neoplastic tumor, which is characterized by an increase in motility and invasiveness. The Cohen laboratory has developed an epithelial tumor model in which overexpression of the epidermal growth factor receptor gene (EGFR) leads to benign tissue hyperplasia. When combined with other cooperating factors, EGFR overexpression can lead to neoplasia and malignant metastasis. Microarray analysis were performed in normal epithelia, hyperplastic, and neoplastic tumors collected from Drosophila wing imaginal discs to identify genes whose misexpression correlates with tumor progression

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE95613 | GEO | 2018/12/21

REPOSITORIES: GEO

Similar Datasets

2016-06-02 | E-GEOD-82132 | biostudies-arrayexpress
2016-06-02 | GSE82132 | GEO
2016-07-03 | E-GEOD-59156 | biostudies-arrayexpress
2013-08-15 | E-GEOD-42928 | biostudies-arrayexpress
2012-08-24 | E-GEOD-40373 | biostudies-arrayexpress
2014-08-11 | E-GEOD-31413 | biostudies-arrayexpress
2017-01-11 | PXD003632 | Pride
2007-06-30 | E-GEOD-3868 | biostudies-arrayexpress
2021-09-27 | GSE164602 | GEO
2021-09-27 | GSE164597 | GEO