Expression data from CD4-CD8-(DN) thymic cells isolated from WT, Ezh2Δ/Δ, p53Δ/Δ, and Ezh2Δ/Δp53Δ/Δ mice
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ABSTRACT: Loss-of-function mutations in EZH2 are associated with poor outcomes in patients with early T cell precursor ALL (ETP-ALL). To understand how EZH2 insufficiency is involved in the pathogenesis of ETP-ALL, we generated mice compound for both Ezh2 and Trp53 conditional deletions.
ORGANISM(S): Mus musculus
PROVIDER: GSE95655 | GEO | 2017/03/04
SECONDARY ACCESSION(S): PRJNA377843
REPOSITORIES: GEO
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