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Inter-individual variation in genes governing human hippocampal progenitor differentiation is associated with hippocampal volume in adulthood

ABSTRACT: The aim of this study was to investigate the effects of the antidepressants, escitalopram (0 nM, 145 nM, 290 nM, 1160 nM) and nortriptyline (0 nM, 267 nM, 534 nM, 1068 nM), in human hippocampal progenitor cells (HPC0A07/03C), either when proliferating or differentiating. We also considered expression changes occuring when proliferating cells switch to a differentiating state to form young neurons and astrocytes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE95791 | GEO | 2017/03/08

SECONDARY ACCESSION(S): PRJNA378418

REPOSITORIES: GEO

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