Genomics

Dataset Information

0

Expression data from pmel1 CD8+ T cells stimulated with agonist anti-CD27, blockade of PD-1/L1 or both together


ABSTRACT: CD8+ T cells are regulated by inhibitory and activatory receptors. We have investigated the influence of enforced CD27 stimulation compared with blockade of PD-1 and the combination of both agents together. Anti-CD27 and PD-1 blockade combined to enhance CD8+ T-cell accumulation, effector protein expression and tumor therapy. This array was used to further characterize the transcriptional changes in CD8+ T cells that drive this differentiation.

ORGANISM(S): Mus musculus

PROVIDER: GSE96923 | GEO | 2018/03/27

REPOSITORIES: GEO

Similar Datasets

2023-06-16 | MSV000092193 | MassIVE
2010-10-03 | E-GEOD-24081 | biostudies-arrayexpress
2017-11-01 | GSE98640 | GEO
2010-10-03 | E-GEOD-24026 | biostudies-arrayexpress
2022-02-18 | GSE192591 | GEO
2020-05-01 | GSE145896 | GEO
2018-05-04 | GSE113987 | GEO
| PRJNA507717 | ENA
2015-05-01 | E-GEOD-65041 | biostudies-arrayexpress
2020-07-10 | GSE129251 | GEO