Genome-wide nucleosome occupancy and DNA methylation profiling in endometriosis cells

ABSTRACT: We show that knocking down ARID1A in an immortalized endometriosis cell line leads to phenotypic changes in vitro. Additionally, we find strong increases in the active H3K27ac mark in promoter regions but decrease of H3K27ac at potential enhancers with targeted DNA methylation-independent alterations in nucleosome occupancy.

ORGANISM(S): Homo sapiens

PROVIDER: GSE97373 | GEO | 2017/04/05

SECONDARY ACCESSION(S): PRJNA381543

REPOSITORIES: GEO