Striatal transcriptome analysis of Shank3-overexpressing mice

ABSTRACT: Shank3 is a core excitatory postsynaptic protein enriched in the striatum. We have previously generated and characterized Shank3-overexpressing transgenic mice, and found that these mice exhibited manic-like behavioral phenotypes. To understand molecular mechanisms underlying the behavioral changes, we performed transcriptome (RNA-sequencing) analysis of the striatal tissues from 12-week-old wild-type and Shank3 transgenic mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE97544 | GEO | 2017/08/17

SECONDARY ACCESSION(S): PRJNA382260

REPOSITORIES: GEO