Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 4000 (Homo sapiens)
SUBMITTER: Yangfei Xiang
PROVIDER: GSE97880 | GEO | 2017-07-21
SECONDARY ACCESSION(S): PRJNA383297
REPOSITORIES: GEO
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GSE97880_RAW.tar | Raw | |||
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Xiang Yangfei Y Tanaka Yoshiaki Y Patterson Benjamin B Kang Young-Jin YJ Govindaiah Gubbi G Roselaar Naomi N Cakir Bilal B Kim Kun-Yong KY Lombroso Adam P AP Hwang Sung-Min SM Zhong Mei M Stanley Edouard G EG Elefanty Andrew G AG Naegele Janice R JR Lee Sang-Hun SH Weissman Sherman M SM Park In-Hyun IH
Cell stem cell 20170727 3
Organoid techniques provide unique platforms to model brain development and neurological disorders. Whereas several methods for recapitulating corticogenesis have been described, a system modeling human medial ganglionic eminence (MGE) development, a critical ventral brain domain producing cortical interneurons and related lineages, has been lacking until recently. Here, we describe the generation of MGE and cortex-specific organoids from human pluripotent stem cells that recapitulate the develo ...[more]