Genomics

Dataset Information

31

The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): Illumina HiSeq 2000 (Arabidopsis thaliana)

SUBMITTER: Heng Zhang  

PROVIDER: GSE98286 | GEO | 2017-04-28

SECONDARY ACCESSION(S): GSE98283PRJNA384584 GSE98285 GSE98284

REPOSITORIES: GEO

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Publications

The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci.

Yang Rong R   Zheng Zhimin Z   Chen Qing Q   Yang Lan L   Huang Huan H   Miki Daisuke D   Wu Wenwu W   Zeng Liang L   Liu Jun J   Zhou Jin-Xing JX   Ogas Joe J   Zhu Jian-Kang JK   He Xin-Jian XJ   Zhang Heng H  

Genome biology 20170531 1


<h4>Background</h4>The chromodomain helicase DNA-binding family of ATP-dependent chromatin remodeling factors play essential roles during eukaryote growth and development. They are recruited by specific transcription factors and regulate the expression of developmentally important genes. Here, we describe an unexpected role in non-coding RNA-directed DNA methylation in Arabidopsis thaliana.<h4>Results</h4>Through forward genetic screens we identified PKL, a gene required for developmental regula  ...[more]

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