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Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin

ABSTRACT: The goals of this project are to study the transcriptome profiling (RNA-seq) of human fribroblast cells undergoing H3K27me3 decrease by histone mutants incorporation (H3.1K27A/M vs H3.1wt) or shRNA-mediated knockdown of specific histone H3K27me3 methyl-transferase EZH2 (shEZH2 vs shNC)

ORGANISM(S): Homo sapiens

PROVIDER: GSE98768 | GEO | 2018/04/24

REPOSITORIES: GEO

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