Resistance to Palbociclib involves multiple mechanisms amenable to targeting with drug holidays or drug switching to improve therapeutic outcome [Illumina]
Ontology highlight
ABSTRACT: Combination of CDK4/6 inhibitors and endocrine therapy has been shown to improve clinical outcome in advanced estrogen receptor-positive breast cancer. However, not all patients will benefit and relapse is inevitable making the identification of new therapeutic strategies/biomarkers of particular importance.
ORGANISM(S): Homo sapiens
PROVIDER: GSE98987 | GEO | 2020/05/12
REPOSITORIES: GEO
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