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Expression data from the RWPE-1 prostate epithelial cell line overexpressing the miR-183 family cluster

ABSTRACT: The full genomic miR-183 cluster (4.8kb) was cloned into lentiviral vector CD511B-1 with polycistronic GFP. RWPE-1 were transduced with a lentivirus from this vector (RWPE-1 183FC), or a CD511B-1 scrambled control with polycistronic GFP (RWPE-1 control). RWPE-1 were FACS sorted by GFP expression and expanded in culture. In RWPE-1 183FC, the miR-183 family members, miR-182, miR-96, and miR-183 were confirmed to be over-expressed at physioloically relevent levels, similar to the increased expression observed in prostate cancer epithelium.

ORGANISM(S): Homo sapiens

PROVIDER: GSE99134 | GEO | 2017/05/23

SECONDARY ACCESSION(S): PRJNA387408

REPOSITORIES: GEO

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