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De novo epigenetic programs inhibit PD-1 blockade-mediated T-cell rejuvenation [expression]

ABSTRACT: De novo DNA methylation establishes T cell exhaustion and inhibits PD-1 blockade-mediated T-cell rejuvenation. Expression profiling of chronically stimulated WT and Dnmt3a cKO antigen-specific CD8 T cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE99449 | GEO | 2017/06/30

SECONDARY ACCESSION(S): PRJNA388486

REPOSITORIES: GEO

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