Genome-wide DNA methylation profiles of lymphoblastoid cell lines from sex-matched sibling pairs discordant for autism diagnosis

ABSTRACT: The goals of this study were to: 1) investigate changes in DNA methylation in lymphoblastoid cell lines (LCL) from individuals with a specific subtype of ASD and their respective non-autistic siblings, 2) relate the differentially methylated genes to ASD-relevant pathways and functions, and 3) explore the potential for class determination (case-control) biomarkers based on methylation signatures.

ORGANISM(S): Homo sapiens

PROVIDER: GSE99935 | GEO | 2021/03/21

REPOSITORIES: GEO