Metabolomics

Dataset Information

0

GNPS-Salinispora strains agar screening final


ABSTRACT: A HPLC-MS based screening of 124 Salinispora strains, grown on A1 agar, subsequently extracted with 3 different solvents.

INSTRUMENT(S): 6520A Quadrupole Time-of-Flight LC/MS

ORGANISM(S): Salinispora Arenicola Salinispora Tropica Salinispora Pacifica

SUBMITTER: Bradley Moore 

PROVIDER: MSV000078836 | GNPS |

REPOSITORIES: GNPS

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Publications

Prioritizing Natural Product Diversity in a Collection of 146 Bacterial Strains Based on Growth and Extraction Protocols.

Crüsemann Max M   O'Neill Ellis C EC   Larson Charles B CB   Melnik Alexey V AV   Floros Dimitrios J DJ   da Silva Ricardo R RR   Jensen Paul R PR   Dorrestein Pieter C PC   Moore Bradley S BS  

Journal of natural products 20161111 3


In order to expedite the rapid and efficient discovery and isolation of novel specialized metabolites, while minimizing the waste of resources on rediscovery of known compounds, it is crucial to develop efficient approaches for strain prioritization, rapid dereplication, and the assessment of favored cultivation and extraction conditions. Herein we interrogated bacterial strains by systematically evaluating cultivation and extraction parameters with LC-MS/MS analysis and subsequent dereplication  ...[more]

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