Project description:Vancomycin Intermediate Staphylococcus aureus (VISA) strain originated during the prolonged hospitalization, chronic infection and vancomycin treatment. The hospital acquired D712 VISA strain were subjected to various sub-inhibitory concentration of nafcillin in Cation Adjusted Mueller Hinton Broth (CA-MHB) and Roswell Park Memorial Institute (RPMI) medium. The MIC of has dropped from 256 ug/ml to 1ug/ml in CA-MHB and RPMI media respectively. The cells were harvested and expression profiling were measured using RNA sequencing at time point of 03 hours.
Project description:LC-MS/MS data for exometabolomic analysis of Staphylococcus aureus grown in RPMI+10%LB and CA-MHB growth media in the presence & absence of antibiotic (nafcillin).
Project description:LC-MS/MS data for exometabolomic analysis of Staphylococcus aureus grown in RPMI+10%LB and CA-MHB growth media in the presence & absence of antibiotic (nafcillin).
Project description:This is a repository of LC/MS, HPLC, BPC data collected from Staphylococcus aureus TCH1516 grown in RPMI (+10%LB) and CA-MHB. Stains were treated with nafcillin.