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Selaginella tamariscina GNPS-based dereplication

ABSTRACT: This is a dataset used for the dereplication of selaginellin derivatives from Selaginella tamariscina.

INSTRUMENT(S): Xevo G2 Q-Tof

ORGANISM(S): Selaginella Tamariscina (ncbitaxon:137178)

SUBMITTER: Kyo Bin Kang

PROVIDER: MSV000083197 | GNPS | Fri Dec 07 00:37:00 GMT 2018

REPOSITORIES: GNPS

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Publications

Molecular Networking Reveals the Chemical Diversity of Selaginellin Derivatives, Natural Phosphodiesterase-4 Inhibitors from Selaginella tamariscina.

Woo Sunmin S Kang Kyo Bin KB Kim Jinwoong J Sung Sang Hyun SH

Journal of natural products 20190621 7

Selaginellins are unique pigments found in the genus Selaginella, the largest genus of Lycopodiophyta. Recent studies reported that some selaginellin analogues have potent phosphodiesterase-4 (PDE4) inhibitory activity. In this study, the chemical diversity of natural selaginellin derivatives was revealed by an MS/MS molecular networking-based dereplication of the Selaginella tamariscina extract. It led to the prioritization of chromatographic peaks predicted as previously unknown ...[more]

PMID: 31244143

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