Metabolomics,Multiomics

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GNPS - Chevrette et al 2019 Insect-associated Streptomyces

ABSTRACT: Paper title: The antimicrobial potential of Streptomyces from insect microbiomes. Author list: Chevrette MG, Carlson CM, Ortega HE, Thomas C, Ananiev GE, Barns KJ, Book AJ, Cagnazzo J, Carlos C, Flanigan W, Grubbs KJ, Horn HA, Hoffmann FM, Klassen JL, Knack JJ, Lewin GR, McDonald BR, Muller L, Melo WGP, Pinto-Tomas AA, Schmitz A, Wendt-Pienkowski E, Wildman S, Zhao M, Zhang F, Bugni TS, Andes DR, Pupo MT, Currie CR. Citation: Nat Commun. 2019 Jan 31;10(1):516. doi: 10.1038/s41467-019-08438-0. PMID: 30705269 mzXMLs from Chevrette et al 2019

INSTRUMENT(S): Bruker maXis ESI Quadrupole TOF

ORGANISM(S): Kitasatospora (ncbitaxon:2063) Gordonia <actinomycete> (ncbitaxon:2053) Pseudonocardia (ncbitaxon:1847) Streptomyces (ncbitaxon:1883)

SUBMITTER: Marc Chevrette  

PROVIDER: MSV000084723 | GNPS | Wed Dec 18 15:58:00 GMT 2019

REPOSITORIES: GNPS

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Antimicrobial resistance is a global health crisis and few novel antimicrobials have been discovered in recent decades. Natural products, particularly from Streptomyces, are the source of most antimicrobials, yet discovery campaigns focusing on Streptomyces from the soil largely rediscover known compounds. Investigation of understudied and symbiotic sources has seen some success, yet no studies have systematically explored microbiomes for antimicrobials. Here we assess the distinct evolutionary  ...[more]

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