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GNPS-acute stage Chagas disease carnitine treatment, large intestine (positive mode)

ABSTRACT: Large intestine samples from mice infected with 50,000 Trypanosoma cruzi parasites or left uninfected. One week post-infection, mice were treated with carnitine, benznidazole or vehicle. Animals were euthanized after 10 days of treatment and organs collected. Metabolites were extracted with 50% methanol followed by 3:1 dichloromethane-methanol and analyzed by C8 chromatography, with positive mode ddMS2 data collection (data-dependent).

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Trypanosoma Cruzi (ncbitaxon:5693) Mus Musculus (ncbitaxon:10090)

SUBMITTER: Laura-Isobel McCall

PROVIDER: MSV000085142 | GNPS | Tue Mar 24 09:42:00 GMT 2020

REPOSITORIES: GNPS

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