Metabolomics

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GNPS Metabolomics of Amaranthus tuberculatus (whole-plant assay)


ABSTRACT: Resistance to a non-selective HPPD-inhibiting herbicide syncarpic acid-3 (SA3) in populations of waterhemp (Amaranthus tuberculatus) (whole-plant assay) revealed using untargeted metabolomics via LC-MS.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Amaranthus Tuberculatus (ncbitaxon:277990)

SUBMITTER: Jeanaflor Crystal T. Concepcion   Dean E. Riechers   Shiv S. Kaundun  

PROVIDER: MSV000087123 | GNPS | Mon Mar 29 09:18:00 BST 2021

REPOSITORIES: GNPS

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Publications

Resistance to a nonselective 4-hydroxyphenylpyruvate dioxygenase-inhibiting herbicide via novel reduction-dehydration-glutathione conjugation in Amaranthus tuberculatus.

Concepcion Jeanaflor Crystal T JCT   Kaundun Shiv S SS   Morris James A JA   Hutchings Sarah-Jane SJ   Strom Seth A SA   Lygin Anatoli V AV   Riechers Dean E DE  

The New phytologist 20210929 5


Metabolic resistance to 4-hydroxyphenylpyruvate dioxygenase (HPPD)-inhibiting herbicides is a threat in controlling waterhemp (Amaranthus tuberculatus) in the USA. We investigated resistance mechanisms to syncarpic acid-3 (SA3), a nonselective, noncommercial HPPD-inhibiting herbicide metabolically robust to Phase I oxidation, in multiple-herbicide-resistant (MHR) waterhemp populations (SIR and NEB) and HPPD inhibitor-sensitive populations (ACR and SEN). Dose-response experiments with SA3 provide  ...[more]

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