Dataset Information

GNPS - Ethanolic extracts of unlabeled and 13C labeled yeast and mixtures thereof

ABSTRACT: Ethanolic extracts of unlabeled and fully 13C labeled yeast (Pichia pastoris) and mixtures thereof were measured on HILIC and C18 (Dual injection system with HILIC eluting until 15 min and RPC after 15 min).

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Komagataella Phaffii (ncbitaxon:460519)

SUBMITTER: Gunda Koellensperger Yasin El Abiead

PROVIDER: MSV000089018 | GNPS | Tue Mar 08 06:29:00 GMT 2022

REPOSITORIES: GNPS

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Publications

Heterogeneous multimeric metabolite ion species observed in LC-MS based metabolomics data sets.

El Abiead Yasin Y Bueschl Christoph C Panzenboeck Lisa L Wang Mingxun M Doppler Maria M Seidl Bernhard B Zanghellini Jürgen J Dorrestein Pieter C PC Koellensperger Gunda G

Analytica chimica acta 20220908

Covalent or non-covalent heterogeneous multimerization of molecules associated with extracts from biological samples analyzed via LC-MS are quite difficult to recognize/annotate and therefore the prevalence of multimerization remains largely unknown. In this study, we utilized 13C labeled and unlabeled Pichia pastoris extracts to recognize heterogeneous multimers. More specifically, between 0.8% and 1.5% of the biologically-derived features detected in our experiments were confirmed to be hetero ...[more]

PMID: 36156231

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