Dataset Information
GNPS - Data files for manuscript - Selected ion monitoring for orbitrap-based metabolomics
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Mus Musculus (ncbitaxon:10090)
SUBMITTER: 
Joshua Rabinowitz
PROVIDER: MSV000094084 | GNPS | Wed Feb 14 09:26:00 GMT 2024
REPOSITORIES: GNPS
Publications
Selected Ion Monitoring for Orbitrap-Based Metabolomics.
Metabolites 20240325 4
Orbitrap mass spectrometry in full scan mode enables the simultaneous detection of hundreds of metabolites and their isotope-labeled forms. Yet, sensitivity remains limiting for many metabolites, including low-concentration species, poor ionizers, and low-fractional-abundance isotope-labeled forms in isotope-tracing studies. Here, we explore selected ion monitoring (SIM) as a means of sensitivity enhancement. The analytes of interest are enriched in the orbitrap analyzer by using the quadrupole ...[more]
