Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GNPS - Bile extracts from 75 animals

ABSTRACT: This dataset consists of data collected in positive ionization mode profiling bile extracts from 75 different animal species. MS/MS data acquisition was carried out on a Thermo Q Exactive mass spectrometer in positive ionization mode, with chromatographic separation achieved using a Phenomenex Polar C18 column.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Animalia

SUBMITTER: Pieter C Dorrestein

PROVIDER: MSV000097131 | GNPS | Sun Feb 16 08:23:00 GMT 2025

REPOSITORIES: GNPS

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

GNPS - Bile Extracts from over 1600 animals Positive mode

Project description:This dataset consists of data collected in positive mode profiling over 1600 different animal species bile extracts.

2020-03-19 | MSV000085120 | GNPS

GNPS-Taurine supplementation in mice study

Project description:This dataset consists of untargeted LC-MS/MS metabolomics data from blood samples collected from mice supplemented with unlabeled and 13C-labeled taurine. MS/MS data acquisition was carried out on Thermo Q Exactive mass spectrometer in positive ionization mode, with chromatographic separation achieved using a Phenomenex Polar C18 column.

2026-01-26 | MSV000100596 | GNPS

A long noncoding RNA landscape in breast cancer reveals a potential role for lncRNA AC009283.1 in proliferation and apoptosis in HER2-enriched molecular subtype

Project description:We silenced lncRNA AC009283.1 using shRNAs in cell line SKBR3, carried a ~75% silencing compared to thenegative control (NC). We evaluated the role of lncRNA AC009283.1 on oncogenic phenotypes in the HER2-enriched SKBR3 breast cancer cell line model. The knockdown of lncRNA AC009283.1 was achieved with ~75% of silencing efficiency. A complete transcriptomic analysis after silencing of lncRNA AC009283.1 revealed an impact on the global expression.

2020-08-12 | GSE134254 | GEO

FAM83H-AS1 silencing in MCF7 breast cancer cells

Project description:We silenced FAM83H-AS1 shRNAs in cell line MCF7 carried a ~75% silencing compared to thenegative control (NC). We evaluated the role of FAM83H-AS1 on oncogenic phenotypes in the MCF7 breast cancer cell line model. The knockdown of FAM83H-AS1 was achieved with ~75% of silencing efficiency. A complete transcriptomic analysis after silencing of FAM83H-AS1 revealed an impact on the global expression.

2020-12-12 | GSE135466 | GEO

EthaNASH_study__healthy_plasma

Project description:This dataset consists of plasma from patients with NASH disease and healthy age- and BMI- matched healthy volunteers with data acquired on Orbitrap in positive ionization mode.

2023-10-09 | MSV000093072 | MassIVE

GNPS - Bile Salt Hydrolase Screening with bile acid and amines

Project description:120 Bile Salt Hydrolases (BSH) and Penicillin V Acylase (PVA) enzymes from various microbial strains were overexpressed in E. coli and purified using nickel affinity chromatography. Enzyme assays were performed by incubating the purified enzymes with 18 bile acids and 49 amines. Following incubation, the reactions were quenched, and the extracts were dried and reconstituted in 80% methanol containing an internal standard. MS/MS data acquisition was carried out on Thermo Exploris 240 mass spectrometer in positive ionization mode, with chromatographic separation achieved using a Phenomenex Polar C18 column.

2025-04-18 | MSV000097665 | GNPS

Silencing of lnc-klhdc7b in the HCC1187 cell line

Project description:By using shRNAs the lnc-klhdc7b was silenced in the cell line HCC1187, the shRNA-1 carried a ~75% silencing compared to the negative control (NC). We evaluated the role of LncKLHDC7B on oncogenic phenotypes in the IM breast cancer HCC1187 cell line model. The knockdown of LncKLHDC7B was achieved with ~75% of silencing efficiency. A complete genomic analysis of the transcriptomic state after silencing of LncKLHDC7B revealed an impact on the global expression of transcripts

2019-03-20 | GSE114468 | GEO

GNPS-Untargeted metabolomics on samples from a genetic mouse model of Primary Sclerosing Cholangitis (PSC).

Project description:Liver, ileum, cecum, colon, serum, feces, and bile juice samples were collected from the 36 mice. MS/MS data acquisition was carried out on a Thermo Q Exactive mass spectrometer in positive ionization mode, with chromatographic separation achieved using a Phenomenex Polar C18 column.

| MSV000099062 | GNPS

GNPS - Pilot Bile Salt Hydrolase Screening with different substrates

Project description:Bile Salt Hydrolases (BSH) and Penicillin V Acylase (PVA) enzymes from various microbial strains were overexpressed in E. coli and purified using nickel affinity chromatography. Enzyme assays were performed by incubating the purified enzymes with bile acids and amines. Following incubation, the reactions were quenched, and the extracts were dried and reconstituted in 50% methanol containing an internal standard. MS/MS data acquisition was carried out on a Q Exactive mass spectrometer in positive ionization mode, with chromatographic separation achieved using a Phenomenex Polar C18 column.

2024-12-11 | MSV000096644 | GNPS

GNPS - Pilot Bile Salt Hydrolase Screening with different substrates

2024-12-13 | MSV000096661 | GNPS