Project description:In this analysis, we assessed the subtle changes in retinol metabolism during wound healing, by analyzing the proteome of normal and wounded skin in Vitamin A deficient -treated mice using targeted proteomics,analysis, SureQuant.
Project description:In this project, we analysed the proteome of skin wounds to investigate whether a vitamin A-deficient diet influences the wound proteome. To achieve this, we conducted quantitative, unbiased proteomic analysis using data-independent acquisition (DIA) mass spectrometr using skin wounds lysates.
Project description:Physical exercise is beneficial to keep physical and mental health. The molecular mechanisms underlying exercise are still worth exploring.The healthy adult mice after six weeks of moderate-intensity exercise (experimental group) and sedentary mice (control group) were used to perform transcriptomic, proteomic, lactylation modification, and metabolomics analysis. In addition, gene sets related to hypoxia, glycolysis, and fatty acid metabolism were used to aid in the screening of hub genes. The mMCP-counter was employed to evaluate infiltration of immune cells in murine liver tissues.