A proteomic ruler for protein copy number and concentration estimation without spike-in standards.

ABSTRACT: Data from ProteomeXchange, PXD ID: PXD000661. Experiment: TPA_Lung, file: 20120207_EXQ6_JRW_TPA_Lung_28_1_T.mzml. Published as part of Mol Cell Proteomics. 2014 Sep 15 . From the Abstract: {{i}} ... Here we present a novel concept that delivers similar quantitative results directly from deep eukaryotic proteome datasets without any additional experimental steps. We show that the MS-signal of histones can be used as a proteomic ruler because is proportional to the amount of DNA in the sample, which in turn depends of the number of cells ... {{/i}}

INSTRUMENT(S): Instrument

ORGANISM(S): Mus_musculus_viruses, Mouse

DISEASE(S): Not Available

SUBMITTER: Winiewski JR, et al.  

PROVIDER: GPM11210029853 | GPMDB |

REPOSITORIES: GPMDB