Widespread Proteome Remodeling and Aggregation in Aging C. elegans.

ABSTRACT: Data from ProteomeXchange, PXD ID: PXD001364. Experiment: AggregatesSILAC_DAF16_D01, file: 20110921_Velos3_DiWa_SA_Celegans_AggregatesSILAC_DAF16_D01-3.mzml. Published as part of Cell. 2015 May 7;161(4):919-932 . From the Abstract: {{i}} ... Here, we profiled more than 5, 000 proteins along the lifespan of the nematode C. elegans. We find that one-third of proteins change in abundance at least 2-fold during aging, resulting in a severe proteome imbalance ... {{/i}}

INSTRUMENT(S): Instrument

ORGANISM(S): Worm, Escherichia_coli_k_12_substr__mg1655

DISEASE(S): Not Available

SUBMITTER: Walther DM, et al.  

PROVIDER: GPM32310019629 | GPMDB |

REPOSITORIES: GPMDB