The nuclear exosome is active and important during budding yeast meiosis.

ABSTRACT: Data from ProteomeXchange, PXD ID: PXD001239. File: Meiosis_IP_rep.mzml. Published as part of PLoS One. 2014 Sep 11;9(9):e107648 . From the Abstract: {{i}} ... We have analysed the activity of the nuclear exosome during meiosis by deletion of TRF4, which encodes a key component of the exosome targeting complex TRAMP. We find that TRAMP mutants produce high levels of CUTs during meiosis that are undetectable in wild-type cells, showing that the nuclear exosome remains functional for CUT degradation, and we further report that the meiotic exosome complex contains Rrp6 ... {{/i}}

INSTRUMENT(S): Instrument

ORGANISM(S): Yeast

DISEASE(S): Not Available

SUBMITTER: Frenk S, et al.  

PROVIDER: GPM32310019869 | GPMDB |

REPOSITORIES: GPMDB