Molecular consequences of proprotein convertase 1/3 inhibition in macrophages for application to cancer immunotherapy: a proteomic study

ABSTRACT: Data from ProteomeXchange, PXD ID: PXD001984. File: KO_LPS1.mzml. Published as part of Mol Cell Proteomics. 2015 Sep 1 . From the Abstract: {{i}} ... Here, we investigated the intracellular impact of the down-regulation of the proprotein convertase 1/3 in NR8383 macrophages. A complete proteomic study of secretomes and intracellular proteins was undertaken and revealed that inhibition of proprotein convertase 1/3 orient macrophages toward an M1 activated phenotype ... {{/i}}

INSTRUMENT(S): Instrument

ORGANISM(S): Mus_musculus_viruses, Rabbit_calicivirus_australia_1_mic_07_uid33267, Rattus_norvegicus_papillomavirus_1_ees_2009_uid40233, Rat_coronavirus_parker_uid39313, Rat

DISEASE(S): Not Available

SUBMITTER: Duhamel M, et al.  

PROVIDER: GPM32310023533 | GPMDB |

REPOSITORIES: GPMDB