Dataset Information
Transcriptomic and proteomic analysis reveals a core Atg9 interactome in the regulation of yeast macroautophagy
Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces Cerevisiae
SUBMITTER: 
Yu Xue
PROVIDER: PXD012458 | iProX | Sat Jan 19 00:00:00 GMT 2019
REPOSITORIES: iProX
Publications
Atg9-centered multi-omics integration reveals new autophagy regulators in <i>Saccharomyces cerevisiae</i>.
Autophagy 20210315 12
In <i>Saccharomyces cerevisiae</i>, Atg9 is an important autophagy-related (Atg) protein, and interacts with hundreds of other proteins. How many Atg9-interacting proteins are involved in macroautophagy/autophagy is unclear. Here, we conducted a multi-omic profiling of Atg9-dependent molecular landscapes during nitrogen starvation-induced autophagy, and identified 290 and 256 genes to be markedly regulated by <i>ATG9</i> in transcriptional and translational levels, respectively. Unexpectedly, we ...[more]
