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Proteomics of Exhaled Breath Condensate in COPD patients

ABSTRACT: Exhaled breath condensate(EBC) is now a safe and clinically significant measurement which has a huge potential to measure biomarkers in COPD. Previous studies profiled the pooled EBC samples from COPD or control participants due to technological limitations. In our study, 32 COPD patients and 28 control individuals were enrolled, and their EBC were collected. After matching with sex, age and smoking history, EBC samples of 19 COPD patients and 19 control individuals were analyzed using tandem mass tags (TMTs) quantitative mass spectrometry individually.

ORGANISM(S): Homo Sapiens

SUBMITTER: Guangfa Wang

PROVIDER: PXD013068 | iProX | Thu Aug 15 00:00:00 BST 2019

REPOSITORIES: iProX

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Proteomics of exhaled breath condensate in stable COPD and non-COPD controls using tandem mass tags (TMTs) quantitative mass spectrometry: A pilot study.

Sun Chao C Zhou Tianyu T Xie Gaoqiang G Fu Shuqian S Gao Lingling L Liao Jiping J Wu Yangfeng Y Wang Guangfa G

Journal of proteomics 20190523

Chronic obstructive pulmonary disease (COPD) is a type of obstructive lung disease characterized by long-term breathing problems and poor airflow. Exhaled breath condensate (EBC) is now a safe and clinically significant measurement which has a huge potential to measure biomarkers in COPD. Previous studies profiled the pooled EBC samples from COPD or control participants due to technological limitations. In our study, 32 COPD patients and 28 control individuals were enrolled, and their EBC were c ...[more]

PMID: 31129269

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