Proteomics

Dataset Information

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In-depth Serum Proteomics in Psoriasis reveals novel biomarkers for disease activity and response to Traditional Chinese Medicine

ABSTRACT: demonstrate the clinical utility of our in-depth serum proteomics platform to identify specific diagnostic and predictive biomarkers for psoriasis, suggesting a great potential for application in translation studies and precision medicine in psoriasis and other immune-mediated diseases

ORGANISM(S): Homo Sapiens

SUBMITTER: Tiannan Guo  

PROVIDER: PXD013089 | iProX | Wed Mar 13 00:00:00 GMT 2019

REPOSITORIES: iProX

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Serum and plasma contain abundant biological information that reflect the body's physiological and pathological conditions and are therefore a valuable sample type for disease biomarkers. However, comprehensive profiling of the serological proteome is challenging due to the wide range of protein concentrations in serum. <b>Methods</b>: To address this challenge, we developed a novel in-depth serum proteomics platform capable of analyzing the serum proteome across ~10 orders or magnitude by combi  ...[more]

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