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Proteome and phosphoproteome profile of acute pancreatitis

ABSTRACT: NP_total or SP_total stand for normal or acute pancreatitis proteome data respectively. NP_phospho or SP_phospho stand for normal or acute pancreatitis phosphoproteome data respectively.

ORGANISM(S): Rattus Norvegicus

SUBMITTER: Bicheng Chen

PROVIDER: PXD015190 | iProX | Tue Aug 27 00:00:00 BST 2019

REPOSITORIES: iProX

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Improved Integrated Whole Proteomic and Phosphoproteomic Profiles of Severe Acute Pancreatitis.

Wang Cheng C Zhang Yanlei Y Tan Jinjuan J Chen Bicheng B Sun Linxiao L

Journal of proteome research 20200427 6

Severe acute pancreatitis (SAP) is caused by complicated biological factors, and revealing its complex pathogenesis by single-target analysis is difficult. Systematic studies have developed slowly because extraction of degradable pancreatic proteins exposed to multiple proteases is challenging. We present integrated whole proteomic and phosphoproteomic profiles of SAP rats based on a modified protein extraction strategy with less protein degradation. Data-dependent acquisition (DDA) and data-ind ...[more]

PMID: 32283030

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