Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Proteomic analysis of Salvia miltiorrhiza root under UV-B treatment

ABSTRACT: The UV-B responsive proteins n root of Salvia miltiorrhiza were systematically analyzed using iTRAQ based proteomic technique

ORGANISM(S): Salvia Miltiorrhiza

SUBMITTER: Xiaojian Yin

PROVIDER: PXD017146 | iProX | Thu Jan 16 00:00:00 GMT 2020

REPOSITORIES: iProX

ACCESS DATA

Json Xml

Similar Datasets

Root-associated microbiota in Salvia miltiorrhiza

Project description:Root-associated microbiota in Salvia miltiorrhiza Metagenome

| PRJNA534198 | ENA

RNA sequencing of HDFs(Human dermal fibroblasts) with or without Sal-B and UVB treatment

Project description:Skin aging is a complex biological process that is influenced by multiple factors, including environmental and genetic factors. Ultraviolet (UV) irradiation can cause short-term sun damage, such as erythema and edema, as well as chronic damage, which accelerates skin aging and produces skin wrinkles and skin laxity. Salvianolic acid B (Sal-B) is the most abundant and bioactive water-soluble extractant from the well-known herbal medicine--Salvia Miltiorrhiza in Chinese traditional medicine. Many studies have found that Sal-B exerts powerful antioxidant and anti-inflammatory effects. Therefore, we speculate that salvianolic acid B may have potential therapeutic value in the aspect of anti-photoaging.

2024-09-14 | GSE243204 | GEO

Deep sequencing identify tissue-specific microRNAs and their target genes involved in tanshinones biosynthesis in Salvia miltiorrhiza

Project description:Salvia miltiorrhiza is one of the most popular traditional medicinal herbs in Asian nations. Its dried root contains a number of tanshinones, protocatechuic aldehyde, salvianolic acid B and rosmarinic, and is used for the treatment of various diseases. To make clear the molecular mechanism of tanshinones biosynthesis in S. miltiorrhiza, the tissue-specific miRNAs and their target genes were identified by high-throughput sequencing and degradome analysis. A total of 452 known miRNAs corresponding to 589 pre-miRNAs, and 40 novel miRNAs corresponding to 24 pre-miRNAs were identified in different tissues of S. miltiorrhiza, respectively. Among them, 62 miRNAs express only in root, 95 miRNAs express only in stem, 19 miRNAs express only in leaf, and 71 miRNAs express only in flower, respectively. By the degradome analysis, 69 targets potentially cleaved by 25 miRNAs were identified. Among them, Acetyl-CoA C-acetyltransferase was identified in S. miltiorrhiza, which was cleaved by miR5072 and involved in the biosynthesis of tanshinones. This study provided valuable information for understanding the tissues expression patterns of miRNAs, and offered a foundation for future studies of the miRNA-mediated tanshinones biosynthesis in S. miltiorrhiza. The tissue-specific miRNAs and their target genes were identified by high-throughput sequencing and degradome analysis.

2015-03-01 | E-GEOD-60757 | biostudies-arrayexpress

Transcriptomic analyses reveal carbon dot-based seed priming in regulation of root growth in rice

Project description:Carbon dots (CDs) can affect plant growth and disease resistance and assist siRNA/DNA delivery. Salvia miltiorrhiza-Derived Carbon Dots were recently found to facilitate plants to adapt to environmental stresses through amplifying Ca2+ signaling and scavenging reactive oxygen species (ROS). More importantly, CDs can be degraded into CO2 and H2O within plant cells, thereby having fewer biosafety issues as compared to those undegradable ones and receiving more attentions in the plant community. However, the molecular mechanisms underlying effects of CD priming on plant growth and development have not been well characterized. In this study, we conducted transcriptomic assays and aim to reveal how CD priming affect root development through transcriptional reprogramming in rice.

2025-05-10 | GSE202652 | GEO

Proteomic and metabonomic analyses to reveal the underlying molecular mechanism of phenolic acids accumulation in leaves of Salvia miltiorrhiza under UV-B radiation

Project description:Salvianolic acid is the secondary metabolic products of Salvia miltiorrhiza, and its biosynthesis is induced and regulated by all kinds of abiotic factors. Our results showed that content of salvianolic acid including caftaric acid, salvianolic acid B, roamarinic acid, and salvianolic acid H was increased more than 50 times by UV-B radiation in leaves of Salvia miltiorrhiza. Further proteomic analysis identified 436 significantly proteins which are contributed to salvianolic acid accumulation under UV-B radiation. Among of them, photosynthesis related proteins were decreased, protein processing and phenolic acids synthesis related confirmed and potential key enzymes including cinnamoyl-CoA reductase, rosmarinic acid synthase, phenylalanine ammonia-lyase, were increased in UV-B treated danshen

2018-04-17 | PXD017135 |

Deep sequencing identify tissue-specific microRNAs and their target genes involved in tanshinones biosynthesis in Salvia miltiorrhiza

2015-03-01 | GSE60757 | GEO

Expression data from five human leukemia cell lines treated with DMSO or tanshinone IIA

Project description:Tanshinone IIA (Tan IIA) is a diterpene quinone extracted from the root of Salvia miltiorrhiza, a Chinese traditional herb. Although previous studies have reported the anti-tumor effects of Tan IIA on various human cancer cells, the underlying mechanisms are not clear. We used microarrays to detail the global programme of gene expression underlying Tan IIA's apoptotic effects on leukemia cells and identified significantly differentially expressed genes (SDEGs).

2011-11-03 | GSE33358 | GEO

Root zone soil of Salvia miltiorrhiza

Project description:Root zone soil of Salvia miltiorrhiza Raw sequence reads

| PRJNA1260604 | ENA

Metabolic features of Cryptosporidium parvum oocysts: Control vs. UV treatment.

Project description:Global gene expression in C. parvum environmental stage (oocysts) and the oocysts treated with UV comparing control untreated ones. Goal was to uncover the metabolic features in oocysts and the oocysts treated with UV. two-condition experiment, UV treatment vs. UV untreatment; two time points, 0.5h and 5h. Each time point, two Biological replicates(1, 2) with two technique replicates(1-1,1-2 ; 2-1, 2-2).

2012-12-31 | E-GEOD-34307 | biostudies-arrayexpress

RNA sequencing of RAW264.7 with or without Sal-B and LPS addition

Project description:Autologous fat grafting (AFG), although an appealing approach to repair soft tissue defects, has various complications. Excessive inflammation at the transplant site is one of the main reasons for the poor effect of fat transplantation and occurrence of complications. Our previous study proved that Salvia miltiorrhiza can enhance fat graft survival. Salvianolic acid B (Sal-B) is the most abundant and bioactive water-soluble compound in Salvia miltiorrhiza and has anti-inflammatory effects on other diseases. Therefore, we hypothesized that salvianolic acid B could improve the effect of fat grafts by inhibiting inflammation.

2023-09-14 | GSE186886 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data