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Plasma proteomics dataset of COVID-19 patients

ABSTRACT: Quantitative proteomic analysis of plasma from different time courses of fatal, severe, and mild COVID-19 patients was performed to assess the biological changes during treatment.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xi Zhou

PROVIDER: PXD019106 | iProX | Mon Jun 22 00:00:00 BST 2020

REPOSITORIES: iProX

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Plasma Proteomics Identify Biomarkers and Pathogenesis of COVID-19.

Shu Ting T Ning Wanshan W Wu Di D Xu Jiqian J Han Qiangqiang Q Huang Muhan M Zou Xiaojing X Yang Qingyu Q Yuan Yang Y Bie Yuanyuan Y Pan Shangwen S Mu Jingfang J Han Yang Y Yang Xiaobo X Zhou Hong H Li Ruiting R Ren Yujie Y Chen Xi X Yao Shanglong S Qiu Yang Y Zhang Ding-Yu DY Xue Yu Y Shang You Y Zhou Xi X

Immunity 20201020 5

The coronavirus disease 2019 (COVID-19) pandemic is a global public health crisis. However, little is known about the pathogenesis and biomarkers of COVID-19. Here, we profiled host responses to COVID-19 by performing plasma proteomics of a cohort of COVID-19 patients, including non-survivors and survivors recovered from mild or severe symptoms, and uncovered numerous COVID-19-associated alterations of plasma proteins. We developed a machine-learning-based pipeline to identify 11 proteins as bio ...[more]

PMID: 33128875

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