Blood serum protein abundance of MDR-TB patients based on data-independent acquisition
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Ji-Cheng Li
PROVIDER: PXD019856 | iProX | Thu Sep 24 00:00:00 BST 2020
REPOSITORIES: iProX
Publications
Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics.
Chen Jing J Han Yu-Shuai YS Yi Wen-Jing WJ Huang Huai H Li Zhi-Bin ZB Shi Li-Ying LY Wei Li-Liang LL Yu Yi Y Jiang Ting-Ting TT Li Ji-Cheng JC
Journal of cellular and molecular medicine 20200923 21
Multidrug-resistant tuberculosis (MDR-TB), defined as tuberculosis (TB) resistant to at least isoniazid and rifampicin, is a major concern of TB control worldwide. However, the diagnosis of MDR-TB remains a huge challenge to its prevention and control. To identify new diagnostic methods for MDR-TB, a mass spectrometry strategy of data-independent acquisition and parallel reaction monitoring was used to detect and validate differential serum proteins. The bioinformatic analysis showed that the fu ...[more]
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