Ontology highlight
ABSTRACT:
ORGANISM(S): Cancer
SUBMITTER: Guowang Xu
PROVIDER: PXD019969 | iProX | Fri Jun 19 00:00:00 BST 2020
REPOSITORIES: iProX
You Lei L Fan Yingying Y Liu Xinyu X Shao Shujuan S Guo Lei L Noreldeen Hamada A A HAA Li Zaifang Z Ouyang Yang Y Li Enyou E Pan Xue X Liu Tianyang T Tian Xin X Ye Fei F Li Xiangnan X Xu Guowang G
Journal of proteome research 20200731 9
Unclarified molecular mechanism and lack of practical diagnosis biomarkers hinder the effective treatment of non-small-cell lung cancer. Herein, we performed liquid chromatography-mass spectrometry-based nontargeted metabolomics analysis in 131 patients with their lung tissue pairs to study the metabolic characteristics and disordered metabolic pathways in lung tumor. A total of 339 metabolites were identified in metabolic profiling. Also, 241 differential metabolites were found between lung car ...[more]