Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: Wenju Liu
PROVIDER: PXD020193 | iProX | Sun Jul 05 00:00:00 BST 2020
REPOSITORIES: iProX
Liu Wenju W Shen Junwei J Shen Junwei J Li Yanfei Y Wu Jiawen J Luo Xiaoli X Yu Yuanyuan Y Zhang Yuhan Y Gu Liang L Zhang Xiaobai X Jiang Cizhong C Li Jue J
Cell death & disease 20210916 10
Acute myocardial infarction (AMI), the leading cause of mortality worldwide, is a rapidly developing and irreversible disease. Therefore, proper prompt intervention at the early stage of AMI is crucial for its treatment. However, the molecular features in the early stage have not been clarified. Here, we constructed mouse AMI model and profiled transcriptomes and proteomes at the early stages of AMI progress. Immune system was extensively activated at 6-h AMI. Then, pyroptosis was activated at 2 ...[more]