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Label free analysis of Bacillus anthracis A16R mutnat strain

ABSTRACT: label free analysis of Bacillus anthracis A16R mutnat strain

ORGANISM(S): Bacillus Anthracis Str. A16r

SUBMITTER: Chunjie Liu

PROVIDER: PXD020800 | iProX | Sun Dec 06 00:00:00 GMT 2020

REPOSITORIES: iProX

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Integrated Transcriptomic and Proteomic Analyses Reveal the Role of NprR in Bacillus anthracis Extracellular Protease Expression Regulation and Oxidative Stress Responses.

Wang Yanchun Y Jiang Na N Wang Bowen B Tao Haoxia H Zhang Xin X Guan Qing Q Liu Chunjie C

Frontiers in microbiology 20201209

NprR is a protein of Bacillus anthracis that exhibits moonlighting functions as either a phosphatase or a neutral protease regulator that belongs to the RNPP family. We previously observed that the extracellular protease activity of an nprR deletion mutant significantly decreased within in vitro cultures. To identify the genes within the regulatory network of nprR that contribute to its protease activity, integrated transcriptomic and proteomic analyses were conducted ...[more]

PMID: 33362738

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